Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress
نویسندگان
چکیده
منابع مشابه
Prevention of Nonalcoholic Steatohepatitis in Rats by Two Manganese-Salen Complexes
Background: Nonalcoholic steatohepatitis (NASH), a progressive stage of nonalcoholic fatty liver disease (NAFLD), is characterized by steatosis with inflammation. Investigations have suggested that oxidative stress may play an important role in the progress of NAFLD to NASH. To provide further insights into beneficial effects of antioxidants in NASH prevention, we employed two manganese-supero...
متن کاملprevention of nonalcoholic steatohepatitis in rats by two manganese-salen complexes
background: nonalcoholic steatohepatitis (nash), a progressive stage of nonalcoholic fatty liver disease (nafld), is characterized by steatosis with inflammation. investigations have suggested that oxidative stress may play an important role in the progress of nafld to nash. to provide further insights into beneficial effects of antioxidants in nash prevention, we employed two manganese-superox...
متن کاملPrevention of nonalcoholic steatohepatitis in rats by two manganese-salen complexes.
BACKGROUND Nonalcoholic steatohepatitis (NASH), a progressive stage of nonalcoholic fatty liver disease (NAFLD), is characterized by steatosis with inflammation. Investigations have suggested that oxidative stress may play an important role in the progress of NAFLD to NASH. To provide further insights into beneficial effects of antioxidants in NASH prevention, we employed two manganese-superoxi...
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15 صفحه اولHigh-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice
Nonalcoholic fatty liver disease (NAFLD) is the most frequent histological finding in individuals with abnormal liver-function tests in the Western countries. In previous studies, we have shown that oxidative phosphorylation (OXPHOS) is decreased in individuals with NAFLD, but the cause of this mitochondrial dysfunction remains uncertain. The aims of this study were to determine whether feeding...
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ژورنال
عنوان ژورنال: Journal of Biomedical Science
سال: 2012
ISSN: 1423-0127
DOI: 10.1186/preaccept-1390880962623620